The star has given the full amount of his £25k award prize money to the trust for venues, which operates to save the Britain's grassroots music venues.
The star was presented with the prize on October 16 as his third album the album was chosen as the outstanding release of the previous year.
He has opted to hand the money over to the Music Venues Trust, in appreciation of the essential function grassroots venues played in his beginning days.
"As an artist would not have achieved this success if it wasn't for all the performances I did around the region, and further afield, when I was just getting going," stated the artist. "These spaces are iconic, but they are in difficulty."
From early 2023 onward, at least 150 of these venues have shut down – roughly 16% of the entire UK sector.
Recently, well-known musicians such as Pulp, Coldplay, Katy Perry and Sheeran have all aided the trust in its attempts to support the industry, by adding a small levy to their ticket costs, which benefits local stages.
Fender also participated, collecting more than £100,000 on his 2024 arena tour to help 38 small stages across Britain.
The donation supported spaces that were dealing with potential shutdown due to difficulties arising from floods, fires and personal losses, as well as regulatory hurdles, court cases and neighbor objections.
Additional spaces received funding support in upgrading amenities and sound and lighting systems that directly benefitted musicians and fans.
"The concept that money from shows in major spaces helps the local stages, where it kicks off for performers like me, is just common sense," Sam Fender has said.
The musician is not the first artist to contribute his Mercury Prize prize money to good deeds.
In Pulp received the award in 1996 for their record their work, frontman the singer announced that the act would donate their cash to the organization the charity.
During 2002, artist the artist divided her prize across a few good causes, including the NSPCC and a charity for Sickle Cell.
"Additionally, I gave a grand to Highgate Newtown, to their classes, because I practiced gymnastics when I was younger and they lacked new equipment," she told the media.
Two years ago, Ezra Collective donated their prize money to the youth organization that nurtured their act, in addition to other local music groups.
And winners that year they gave their award to a charity for MS after a acquaintance was found to have the condition.
"Winning was quite enough," remarked singer Heather Small. "The money was the extra but we didn't require the bonus, because we had the main prize. So our success impacted somebody else's life."
Recently, the Music Venues Trust revealed it had protected a couple of grassroots venues in south-east England, by bringing them into public stewardship.
The first in Southampton and The Croft in the city were acquired under the Own Our Venues scheme, which is funded by Arts Council England and music fans who purchase "stakes" in the venues.